AIM2 forms a complex with pyrin and ZBP1 to drive PANoptosis and host defence

3 September 2021 0 By Bambam

Nature, Published online: 01 September 2021; doi:10.1038/s41586-021-03875-8

AIM2 responds to infection with herpes simplex virus 1 or Francisella novicida by driving assembly of a large multi-protein complex containing multiple inflammasome sensors and cell death regulators.