Using DNA sequencing data to quantify T cell fraction and therapy response

11 September 2021 0 By Bambam

Nature, Published online: 08 September 2021; doi:10.1038/s41586-021-03894-5

A robust, cost-effective technique based on whole-exome sequencing data can be used to characterize immune infiltrates, relate the extent of these infiltrates to somatic changes in tumours, and enables prediction of tumour responses to immune checkpoint inhibition therapy.